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Freakonomics Radio

Freakonomics Radio

Discover the hidden side of everything with Stephen J. Dubner, co-author of the Freakonomics books. Each week, Freakonomics Radio tells you things you always thought you knew (but didn’t) and things you never thought you wanted to know (but do) — from the economics of sleep to how to become great at just about anything. Dubner speaks with Nobel laureates and provocateurs, intellectuals and entrepreneurs, and various other underachievers.

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56 min
Today

615. Is Ozempic as Magical as It Sounds?

In a wide-ranging conversation with Ezekiel Emanuel, the policymaking physician and medical gadfly, we discuss the massive effects of GLP-1 drugs like Ozempic, Wegovy, and Mounjaro. We also talk about the state of cancer care, mysteries in the gut microbiome, flaws in the U.S. healthcare system — and what a second Trump term means for healthcare policy. SOURCES:Ezekiel Emanuel, vice provost for Global Initiatives, co-director of the Health Transformation Institute, and professor at the University of Pennsylvania Perelman School of Medicine. RESOURCES:"Obesity Drugs Would Be Covered by Medicare and Medicaid Under Biden Proposal," by Margot Sanger-Katz (The New York Times, 2024)."International Coverage of GLP-1 Receptor Agonists: A Review and Ethical Analysis of Discordant Approaches," by Johan L. Dellgren, and Govind Persad, and Ezekiel J. Emanuel (The Lancet, 2024).The Coming Wave: Technology, Power, and the Twenty-first Century's Greatest Dilemma, by Mustafa Suleyman (2023)."The Significance of Blockbusters in the Pharmaceutical Industry," by Alexander Schuhmacher, Markus Hinder, Nikolaj Boger, Dominik Hartl, and Oliver Gassmann (Nature Reviews Drug Discovery, 2022).Reinventing American Health Care: How the Affordable Care Act Will Improve Our Terribly Complex, Blatantly Unjust, Outrageously Expensive, Grossly Inefficient, Error Prone System, by Ezekiel J. Emanuel (2014)."Why I Hope to Die at 75," by Ezekiel J. Emanuel (The Atlantic, 2014)."Direct-to-Consumer Advertising of Pharmaceuticals," by Ziad F. Gellad and Kenneth W. Lyles (The American Journal of Medicine, 2014).Brothers Emanuel: A Memoir of an American Family, by Ezekiel J. Emanuel (2013)."Bounds in Competing Risks Models and the War on Cancer," by Bo E. Honoré and Adriana Lleras-Muney (Econometrica, 2006). EXTRAS:"How to Fix Medical Research," by People I (Mostly) Admire (2024)."The Suddenly Diplomatic Rahm Emanuel," by Freakonomics Radio (2023)."Ari Emanuel Is Never Indifferent," by Freakonomics Radio (2023)."Who Pays for Multimillion-Dollar Miracle Cures?" by Freakonomics, M.D. (2023)."Who Gets the Ventilator?" by Freakonomics Radio (2020).

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43 min
7 Nov

610. Who Wins and Who Loses Once the U.S. Legalizes Weed?

Some people want the new cannabis economy to look like the craft-beer movement. Others are hoping to build the Amazon of pot. And one expert would prefer a government-run monopoly. We listen in as they fight it out. (Part four of a four-part series.) SOURCES:Jon Caulkins, professor of operations research and public policy at Carnegie Mellon University.Adam Goers, senior vice president of The Cannabist Company and chairperson of the Coalition for Cannabis Scheduling Reform.Yasmin Hurd, director of the Addiction Institute at Mount Sinai.Jared Polis, governor of Colorado.Ryan Stoa, associate professor of law at Louisiana State University. RESOURCES:"Prevalence of and Trends in Current Cannabis Use Among U.S. Youth and Adults, 2013–2022," by Delvon T. Mattingly, Maggie K. Richardson, and Joy L. Hart (Drug and Alcohol Dependence Reports, 2024)."Colorado’s Weed Market Is Coming Down Hard and It’s Making Other States Nervous," by Mona Zhang (Politico, 2024)."Reducing Alcohol Consumption, the Nordic Way: Alcohol Monopolies, Marketing Bans and Higher Taxation," by the World Health Organization (2023)."Economic Benefits and Social Costs of Legalizing Recreational Marijuana," by Jason P. Brown, Elior Cohen, and Alison Felix (Federal Reserve Bank of Kansas City Research Working Paper, 2023)."Competition in the Markets for Beer, Wine, and Spirits," by the United States Department of the Treasury (2022)."Alcohol Monopolies," by Robin Room (Scottish Health Action on Alcohol Problems, 2021)."Craft Beer Is the Strangest, Happiest Economic Story in America," by Derek Thompson (The Atlantic, 2018)."Marijuana Discontinuation, Anxiety Symptoms, and Relapse to Marijuana," by Marcel O. Bonn-Miller and Rudolf H. Moos (Addictive Behaviors, 2009). EXTRAS:"Is America Switching from Booze to Weed?" series by Freakonomics Radio (2024)."Why Do Your Eyeglasses Cost $1,000?" by Freakonomics Radio (2024)."Should You Trust Private Equity to Take Care of Your Dog?" by Freakonomics Radio (2023)."Is Dialysis a Test Case of Medicare for All?" by Freakonomics Radio (2021).

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